President Barack Obama on Tuesday signed the 21st Century Cures Act into law, authorizing $6.3 billion in biomedical research funding—$4.8 billion of which will go to the National Institutes of Health.

NIH’s high-ticket items funded by the law include $1.8 billion for Vice President Joe Biden’s Cancer Moonshot, $1.6 billion for the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, and $1.4 billion for President Obama’s Precision Medicine Initiative.

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